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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPF1
All Species:
21.82
Human Site:
T218
Identified Species:
40
UniProt:
O43516
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43516
NP_001070737.1
503
51275
T218
R
Q
P
S
P
G
P
T
P
P
P
F
P
G
N
Chimpanzee
Pan troglodytes
XP_001150374
510
51924
T218
R
Q
P
S
P
G
P
T
P
P
P
F
P
G
N
Rhesus Macaque
Macaca mulatta
XP_001090880
510
52064
T218
R
Q
P
G
P
G
P
T
P
P
P
F
P
G
N
Dog
Lupus familis
XP_545531
517
52682
T230
R
Q
P
S
P
G
P
T
P
P
P
F
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1I7
493
50062
F215
L
G
A
P
R
P
P
F
P
G
N
R
G
A
A
Rat
Rattus norvegicus
Q6IN36
487
49732
F210
L
G
A
P
R
P
P
F
P
G
N
R
G
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515714
498
50998
T214
R
Q
P
N
L
G
P
T
P
P
P
F
P
G
H
Chicken
Gallus gallus
NP_001012935
494
49866
T210
R
Q
P
S
L
G
P
T
P
P
P
F
P
G
S
Frog
Xenopus laevis
NP_001079978
426
44520
D158
A
H
R
P
S
L
P
D
L
T
R
P
P
S
S
Zebra Danio
Brachydanio rerio
XP_001919866
485
49016
P207
S
A
P
T
P
P
P
P
T
L
P
G
R
Q
P
Tiger Blowfish
Takifugu rubipres
NP_001098701
410
41639
P142
A
A
P
P
P
P
V
P
N
G
G
R
P
P
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195725
392
41038
N122
S
Q
P
Q
N
T
H
N
P
V
S
A
R
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37370
817
82575
Q191
A
S
A
P
K
V
P
Q
N
R
P
H
M
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.6
85.8
N.A.
88.6
87.4
N.A.
80.9
73.1
40.5
58.6
39.3
N.A.
N.A.
N.A.
35.9
Protein Similarity:
100
98.2
97.6
90.3
N.A.
92
91.6
N.A.
87.2
82.1
50.5
68.1
48.3
N.A.
N.A.
N.A.
42.5
P-Site Identity:
100
100
93.3
93.3
N.A.
13.3
13.3
N.A.
80
86.6
13.3
26.6
20
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
100
N.A.
13.3
13.3
N.A.
93.3
93.3
20
33.3
20
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
16
24
0
0
0
0
0
0
0
0
8
0
16
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
47
0
0
0
% F
% Gly:
0
16
0
8
0
47
0
0
0
24
8
8
16
47
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
0
0
16
8
0
0
8
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
8
0
0
8
16
0
16
0
0
0
24
% N
% Pro:
0
0
70
39
47
31
85
16
70
47
62
8
62
16
8
% P
% Gln:
0
54
0
8
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
47
0
8
0
16
0
0
0
0
8
8
24
16
0
0
% R
% Ser:
16
8
0
31
8
0
0
0
0
0
8
0
0
8
39
% S
% Thr:
0
0
0
8
0
8
0
47
8
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _